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酶联免疫吸附试验与化学发光法检测乙型肝炎病毒血清标志物的对比分析

王立

医学信息Issue(18):259-260,2.
医学信息Issue(18):259-260,2.

酶联免疫吸附试验与化学发光法检测乙型肝炎病毒血清标志物的对比分析

Comparative Analysis of ELISA and Chemiluminescent Detection of HBV Serological Markers

王立1

作者信息

  • 1. 泰州市第三人民医院,江苏 泰州 225300
  • 折叠

摘要

Abstract

Objective Compare the detection of serum Hepetitis B virus markers (serum HBsAg, HBsAb, HBeAg, HBeAb and HBcAb) by enzyme-linked immunosorbent assay (ELISA) and chemiluminescence immunoassay (CLIA). Methods Serum samples of two hundreds outpatients in our infection department were col ected. Each sample were detected by ELISA and CLIA analysis, the data were statistical y analyzed with chi-square tests. Results The value of HBsAg, HBsAb, HBeAg, HBeAb and HBcAb was 0.25ng/ml, 9.8mIU/ml, 0.1Ncu/ml, 1Ncu/ml and 0.6 Ncu/ml, respectively, al significantly higher than the value detected by CLIA. The positive rate by CLIA was lower than ELISA. Conclusion The quantitative analyze of HBV-M by CLIA has a high sensitivity than ELISA, which indicated a bet er guiding significance of CLIA in clinical.

关键词

肝炎/乙型肝炎病毒/酶联免疫吸附试验/化学发光检测法

Key words

Hepatitis/Hepatitis B virus/Enzyme-linked immunosorbent assay/Chemiluminescence immunoassay

引用本文复制引用

王立..酶联免疫吸附试验与化学发光法检测乙型肝炎病毒血清标志物的对比分析[J].医学信息,2013,(18):259-260,2.

医学信息

1006-1959

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