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抗结核核药物致超敏反应综合症5例临床分析

崔建立

医学信息Issue(40):46-46,1.
医学信息Issue(40):46-46,1.

抗结核核药物致超敏反应综合症5例临床分析

Clinical Analysis of 5 Cases of Anti Tuberculosis Drug Induced Hypersensitivity Syndrome

崔建立1

作者信息

  • 1. 天津市海河医院,天津 300350
  • 折叠

摘要

Abstract

Objective To characterize the clinical characteristics of drug hypersensitivity syndrome(DHS) caused by anti-TB medicine.Methods Retrospectively analysis the clinical characteristics of 5DHS caused by anti-TB medicine Patients admit ed into Tianjin hai he hospital duri ng June 2012 t o A2014.And the occurrence pat erns of DHS were summarized.Results There were 3 males and 2 females with anage rangeof 18 to 47 years.A1l cases developedskin rashes with fever within 15 to 60 days (n=5).Lymphadenopathy was observed (n=2), facial swel ing Was also appeared (n=3). Eosinophilia Was observed in al cases (n=5).Liver involvement was common (n=5).Glucocorticoids were applied in al cases (n=5).The clinical outcomes included discharging with recovery (n=4),and transfer to another hospital(n=1).Conclusion The clinical manifestations of DHS caused by anti-TB medicine are complicated.IF early detection and treatment with good results.

关键词

抗结核药物/药物过敏/药疹/超敏反应综合征

Key words

Anti tuberculosis drugs/drug al ergy/Drug eruption/Super sensitive reaction syndrome

引用本文复制引用

崔建立..抗结核核药物致超敏反应综合症5例临床分析[J].医学信息,2015,(40):46-46,1.

医学信息

1006-1959

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