摘要
Abstract
Objective To explore the detection and significance of thyroid autoantibodies and thyroid function in pregnant women with gestational diabetes.Methods Selected 46 cases pregnant women with gestational diabetes,they were set as observation group, chose another 43 cases healthy pregnant women as control group, tested and compared thethyroid autoantibodies index of thyroid peroxidase antibodies (TPOAb) and anti thyroglobulin (TGAb), and thyroid function index and promote thyroxine (TSH), three iodine thyroid glycine (T3), thyroxine (T4), free three iodine thyroid glycine (FT3) and free thyroxine (FT4) between two groups , compared the thyroid autoantibodies positive situation between two groups. Results There were 3 cases positive pregnant women with TGAb,6 cases with TPOAb,2cases both with TGAb and TPOAb in observation group,the positive rate was 23.91%;There were 1case positive pregnant women with TGAb,1 case with TPOAb, the positive rate was 4.65%, the dif erences had statistical significance between groups ( <0.05);The level of FT4 in observation group was(5.24±0.89) pmol/L,it was significantly lower than in the control group,the dif erence was statistical y significant ( <0.05);The dif erence was no statistical y significant of TSH, T3, T4, FT3 between two groups ( >0.05). Conclusion The positive rate of thyroid autoantibodies in pregnant women with gestational diabetes is high, and exist thyroid disorders, they need for early screening.关键词
妊娠期糖尿病/甲状腺自身抗体/甲状腺功能Key words
Gestational diabetes/Thyroid autoantibodies/Thyroid function