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新柏氏液基细胞学检测联合细胞DNA定量检测技术在宫颈病变筛查中的应用

孙志刚 孙雷 于霄 王璐 李静

医学信息Issue(44):123-124,2.
医学信息Issue(44):123-124,2.

新柏氏液基细胞学检测联合细胞DNA定量检测技术在宫颈病变筛查中的应用

ThinPrep Cytologic Test and Cell DNA Quantitative Detection Techonology Applicate in Screening of Cervical Lesions

孙志刚 1孙雷 2于霄 2王璐 2李静2

作者信息

  • 1. 大连医科大学附属第一医院病理科,辽宁 大连 116011
  • 2. 大连医科大学病理学与法医学教研室,辽宁 大连 116044
  • 折叠

摘要

Abstract

Objective To investigate the value of ThinPrep cytologic test and cel DNA quantitative detection techonology application in screening of cervical lesions. Methods Col ected 2837 cases between January 2013 and April 2014 in dalian municipal central hospital outpatient.Use TCT test the DNA quantitative detection positive people,and with biopsy histopathology diagnosis as the gold standard, analysis the value of two kinds of techonology applition in screening of cervical lesions. Results TCT detection positive rate was 2.64%, DNA test positive rate was 5.18%, the sensitivity was significantly higher than artificial reading. The coincidence rate of TCT diagnosis and DNA test results respectively with pathological histology diagnosis was 59.09% and 61.36%.Conclusion TCT combined with cel DNA test imprives not only the ef iciency of reading but also the detection of abnomal cel s, thereby reduced false negativity.

关键词

宫颈病变/TCT/细胞DNA定量检测

Key words

Uterine cervical diseases/TCT/Cel DNA quantitative detection

引用本文复制引用

孙志刚,孙雷,于霄,王璐,李静..新柏氏液基细胞学检测联合细胞DNA定量检测技术在宫颈病变筛查中的应用[J].医学信息,2015,(44):123-124,2.

医学信息

1006-1959

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