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精子DNA碎片率对辅助生殖结局的影响

姚晓飞 宋焱鑫 李红芳 董波

医学信息Issue(44):128-129,2.
医学信息Issue(44):128-129,2.

精子DNA碎片率对辅助生殖结局的影响

Effect of Sperm DNA Fragmentation Index on the Outcome of in Vitro Fertilization-embryo Transfer

姚晓飞 1宋焱鑫 1李红芳 1董波1

作者信息

  • 1. 洛阳市妇女儿童医疗保健中心,河南 洛阳471000
  • 折叠

摘要

Abstract

Objective To analyze the ef ect of Sperm DNA fragmentation index on the outcome of in vitro fertilization-embryo transfer (IVF-ET).Methods A retrospective study was conducted in 112 IVF-ET cycles of Institute of Reproduction, Luoyang Women ﹠ Children's Health Care Hospital , among these cycles no women's age were above 35 years old, and the cause of infertility was only fal opion tube factor. The cycles were divided into 3 groups (A, B, C) by dif erent sperm DNA fragmentation index (DFI), outcome of IVF-ET was compared among these groups.Results The fertilization rate of IVF of C group was the lowest ( <0.05), and the good quality embryo rate of IVF of C group was the highest ( <0.05).No dif erence among the 3 groups of cleavage rate, embryo implantation rate and clinical pregnancy rate ( >0.05).Conclusion High sperm DNA fragmentation index reduces the fertilization rate of IVF, the embryo grading standard is not enough to predict outcome, and more research is needed.

关键词

精子DNA碎片率/IVF-ET

Key words

Sperm DNA fragmentation index/Vitro fertilization-embryo transfer

引用本文复制引用

姚晓飞,宋焱鑫,李红芳,董波..精子DNA碎片率对辅助生殖结局的影响[J].医学信息,2015,(44):128-129,2.

基金项目

名称精子DNA结构完整性与辅助生殖相关性研究;编号1302018B ()

医学信息

1006-1959

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