中国当代儿科杂志Issue(10)：1142-1147,6.DOI:10.7499/j.issn.1008-8830.2015.10.025
胎龄<28周早产儿动脉导管未闭的治疗进展
Progress in management of patent ductus arterious in preterm infants with gestational age of <28 weeks
田方(综述) 1石文静(审校)1
作者信息
- 1. 复旦大学附属儿科医院，上海 201102
- 折叠
摘要
Abstract
Patent ductus arteriosus (PDA) is a common problem encountered in the early neonatal period, particularly in preterm infants. Optimal management of PDA in preterm infants remains controversial. Despite considerable historical and physiological data indicating a persistent PDA may be harmful, robust evidence of long-term beneifts or harms from treatment is lacking. This has been equated to a lack of beneift but is also a relfection of the fact that many clinical trials were designed to assess the effects of short-term (2-8 days) rather than prolonged exposure to a PDA. No clinical trials have been designed to assess the effects of prolonged exposure of persistent PDA on morbidity and mortality of very premature infants. Significant changes in management of PDA, i.e., less treatment for PDA, have evolved in recent years. This paper reviews the current literature and evidence for treatment options and research progress of PDA in infants with gestational age of <28 weeks.关键词
动脉导管未闭/治疗/早产儿Key words
Patent ductus arteriosus/Management/Preterm infant引用本文复制引用
田方(综述),石文静(审校)..胎龄<28周早产儿动脉导管未闭的治疗进展[J].中国当代儿科杂志,2015,(10):1142-1147,6.
