中国感染控制杂志Issue(9)：611-613,625,4.DOI:10.3969/j.issn.1671-9638.2015.09.009
社区获得性与医院获得性泌尿道感染病原菌及耐药性
Pathogens and antimicrobial resistance in community-associated and healthcare-associated urinary tract infection
韩广营 1单可记 1陈松婷 1尹建吉 1茆尤尤 1熊辛1
作者信息
- 1. 昆明医科大学第一附属医院，云南 昆明 650032
- 折叠
摘要
Abstract
Objective To analyze the difference in constituent and antimicrobial resistance of pathogens in commu-nity-associated urinary tract infection(CA-UTI)and healthcare-associated UTI(HA-UTI).Methods Clinical data and microbial detection of urine specimens of 960 patients with UTI in a hospital between January 2013 and June 2014 were investigated retrospectively,difference in constituent and antimicrobial resistance of pathogens were ana-lyzed.Results 403 cases were CA-UTI,and 557 were HA-UTI;pathogens in both CA-UTI and HA-UTI were gram-negative bacteria,accounting for 78.16% and 66.97% respectively.Constituent of pathogens in CA-UTI and HA-UTI were significantly different(χ2 =21 .68,P <0.001 ).Resistant rates of Escherichia coli to piperacillin /tazobactam,cefazolin,cefoperazone / sulbactam,aztreonam,meropenem,ertapenem,gentamicin,and compound sulfamethoxazole were all significantly different between CA-UTI and HA-UTI (all P <0.05);Except aztreonam, resistant rates of Escherichia coli in HA-UTI to the other antimicrobial agents were all higher than CA-UTI.Re-sistant rates of Enterococcus faecium in HA-UTI to penicillin,ampicillin,gentamicin,levofloxacin,ciprofloxacin, and moxifloxacin were all higher than CA-UTI(all P <0.05).Conclusion Constituent and antimicrobial resistance of pathogens in CA-UTI and HA-UTI are different,proper antimicrobial agents should be chosen according to con-stituent features of pathogens and change in antimicrobial resistance,so as to prevent and reduce the emergence of drug-resistant strains,and improve therapeutic effectiveness.关键词
泌尿系统感染/医院感染/社区感染/病原菌/抗药性,微生物Key words
urinary system infection/healthcare-associated infection/community-associated infection/pathogen/drug resistance,microbial分类
医药卫生引用本文复制引用
韩广营,单可记,陈松婷,尹建吉,茆尤尤,熊辛..社区获得性与医院获得性泌尿道感染病原菌及耐药性[J].中国感染控制杂志,2015,(9):611-613,625,4.
