中国感染控制杂志Issue(10)：649-653,5.DOI:10.3969/j.issn.1671-9638.2015.10.001
新生儿重症监护病房医院感染流行病学多中心研究
Multicenter study on epidemiology of healthcare-associated infection in neonatal intensive care units
摘要
Abstract
Objective To investigate the epidemiological characteristics of healthcare-associated infection (HAI)in neo-natal intensive care units(NICUs)of tertiary first-class hospitals in China,and provide scientific evidence for the prevention and control of neonatal HAI.Methods 17 hospitals in 9 provinces were selected for multicenter study,HAI occurred in neonates at NICUs from October 2013 to September 2014 were surveyed prospectively according to the uniform diagnostic criteria and methods.Results A total of 12 998 neonates were monitored,436 (3.35%)HAI cases occurred,the total patient-days were 126 125 days,incidence of infection was 3.46/1 000 patient-days.HAI cases rate decreased with the in-crease of birth weight (χ2 =291.55,P <0.001).The difference of HAI rate in neonates at different sizes of ICUs were significantly different(χ2 =49.77,P <0.001),infection case rate and infection incidence per 1 000 patient-days were both highest in NICUs with >30 beds;HAI case rate was highest in southwest region(10.36%),infection rate per 1 000 pa-tient-days was the highest in southern China(10.52‰).Lower respiratory tract and bloodstream were the main infection sites;the major pathogens for infection were Klebsiella pneumoniae ,Escherichia coli ,and Acinetobacter baumannii . Conclusion The incidences of HAI in NICUs are different among neonates of different birth weight,at different sizes of ICUs,and at ICUs of different regions,surveillance should be strengthened,prevention and control measures should imple-mented according to infection characteristics.关键词
新生儿监护病房/NICU/医院感染/例次感染率/日感染率/流行病学/多中心研究Key words
neonatal intensive care unit/healthcare-associated infection/infection case rate/infection rate per 1 000 patient-days/epidemiology/multicenter study分类
医药卫生引用本文复制引用
贾会学,杨芸,刘运喜,文建国,陆群,李六亿,殷环,吴安华,胡必杰,张秀月,侯铁英,宗志勇,李卫光,杨怀..新生儿重症监护病房医院感染流行病学多中心研究[J].中国感染控制杂志,2015,(10):649-653,5.基金项目
中国医院协会医院感染预防与控制能力建设项目 （）
