摘要
Abstract
Objective To evaluate risk factors for multidrug-resistant organisms(MDRO)pulmonary infection in elderly patients in a hospital, and provide scientific basis for prevention and control of MDRO infection. Methods 188 elderly patients who developed pulmonary infection between August 2010 and December 2012 were divided into MDR group (n=95)and non-MDR group (n=93)according to sputum bacterial culture results,clini-cal data of two groups of patients were analyzed.Results 102 strains of MDROs were isolated from patients with MDRO pulmonary infection,the top three were Acinetobacter baumannii (31 .37%),Pseudomonas aeruginosa (25.49%),and methicillin-resistant Staphylococcus aureus (15.69%).Univariate analysis showed that 7 risk fac-tors for MDRO pulmonary infection in elderly patients were history of cerebrovascular disease or dementia,hy-poproteinemia,dysphagia,bedridden,history of ICU hospitalization,recent application of 3,4-generation cephalo-sporins,and invasive procedures.Multivariate logistic regression analysis showed that hypoproteinemia (OR,6.02 [95%CI ,1 .50-24.18]),invasive procedures (OR,6.55 [95%CI,1.69-25.44]),and bedridden (OR,6.03 [95%CI, 1.92-18.91])were independent risk factors for MDRO pulmonary infection in elderly patients.Conclusion Multiple factors contribute to MDRO pulmonary infection in elderly patients,comprehensive prevention and control measures should be taken against the risk factors,so as to prevent and control MRDO pulmonary infection in elderly patients.关键词
老年人/肺炎/病原菌/多重耐药/危险因素/医院感染Key words
the elderly/pneumonia/pathogen/multidrug-resistance/risk factor/healthcare-associated infection分类
医药卫生
