注射用甲泼尼龙琥珀酸钠治疗外伤性脑水肿的疗效与安全性OA北大核心CSCDCSTPCD
Efficacy and safety of methylprednisolone in the treatment of traumatic brain edema
目的：探讨注射用甲泼尼龙琥珀酸钠治疗颅脑外伤性脑水肿临床疗效及安全性。方法选取颅脑外伤患者49例，随机分为试验组23例和对照组26例。试验组，静脉滴注甲泼尼龙琥珀酸钠40 mg＋0.9％生理盐水100 mL，每日2次；对照组，静脉推注地塞米松20 mg，每日2次，2组患者疗程均为7天。分析比较2组患者术后14天内脑水肿情况及术后6个月神经功能恢复情况。结果术后随访6个月，试验组恢复良好8例，死亡3例，对照组恢复良好6例，死亡4例；2组患者临床疗效…查看全部>>
Objective To evaluate the efficacy and safetys of methyl-prednisolone in the treatment of traumatic brain edema.Methods Forty nine patients with traumatic brain edema were included in this study.Of the included 49 cases, 23 patients ( experiment group ) received methyl-prednisolone 40 mg+0.9%normal saline 100 mL intravenous drip bid;26 cases( control group ) treated with dexamethasone 20 mg intravenous bid.The schedule were 7 days for the two groups.The brai…查看全部>>
赵彬;姚鑫
天津医科大学，天津 300070 静海县医院 神经外科，天津 静海 301600
医药卫生
注射用甲泼尼龙琥珀酸钠地塞米松脑水肿预后
methylprednisolonedexamethasonebrain edemaprognosis
《中国临床药理学杂志》 2015 (17)
1716-1717,1735,3
天津市卫生局科技基金资助项目（2011kz07）
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