中国临床药理学杂志Issue(18)：1822-1824,3.DOI:10.13699/j.cnki.1001-6821.2015.18.007
马来酸桂哌齐特治疗肾绞痛的临床疗效及安全性评价
Clinical efficacy and safety evaluation of cinepazide maleate in the treatment of renal colic
摘要
Abstract
Objective To observe the clinical therapeutic effect of cine-pazide maleate in the treatment of renal colic .Methods Seventy -six patients of renal colic were randomly divided into 2 groups.The control group(36 patients) received lornoxicam 8 mg and progesterone 40 mg by intramuscular injection qd.The treatment group ( 40 patients ) received cinepazide maleate 320 mg by intravenous drip qd additionally.The de-gree of pain relief , recurrence and incidence of adverse reactions were observed in 6 h.Results The efficiency and significant efficiency of the treatment group were 100.00%and 92.50%.In contrast , the efficiency and significant efficiency of the control group were 88.89%and 69.44%respectively and the differences were statistically significant .Within 6 hours of treatment, treatment group recurrent rate of renal colic (0), was lower than that of control group ( 13.89%) .The two groups were no obvious adverse reaction of drug associated .Conclusion Cinepazide maleate could obviously relieve renal colic , reduce the recurrence rate , and not lead to significant adverse reactions .So, cinepazide maleate is a new choice for the treatment of renal colic .关键词
肾绞痛/马来酸桂哌齐特/腺苷/氧自由基/解痉Key words
renal colic/cinepazide maleate/adenosine/oxygen free radicals/spasmolysis分类
医药卫生引用本文复制引用
冯宇鹏,叶向东,连学雄,李立,李峰,赵仕佳,廖耀军,吴文正..马来酸桂哌齐特治疗肾绞痛的临床疗效及安全性评价[J].中国临床药理学杂志,2015,(18):1822-1824,3.基金项目
广州医科大学校级科研基金资助项目 （）
