中国临床药理学杂志Issue(20):2080-2083,4.DOI:10.13699/j.cnki.1001-6821.2015.20.031
与结直肠癌转移相关的微小 RNA研究现状
Review of microRNA related to the metastasis of colorectal cancer
摘要
Abstract
Metastasis is one of the leading cause of death in patients with colorectal cancer.MicroRNA ( miRNA) can regulate epithelial-mesen-chymal transition, oncogenes, tumor suppressor genes and tumor metasta-sis related genes, and combine target gene mRNA by binding to comple-mentary sites to regulate the expression of target genes in post-transcrip-tional, thus regulate the tumor occurrence and development.In recent years, more and more studies show that miRNAs play important roles in the metastasis of colorectal cancer, which is expected to become a new target for the treatment of colorectal cancer.关键词
结直肠癌/转移/微小RNA/相关性Key words
colorectal cancer/metastasis/microRNA/relationship分类
医药卫生引用本文复制引用
彭永红,蔡国豪,喻学桥,周卫平..与结直肠癌转移相关的微小 RNA研究现状[J].中国临床药理学杂志,2015,(20):2080-2083,4.基金项目
海南省自然科学基金资助项目 ()