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与结直肠癌转移相关的微小 RNA研究现状

彭永红 蔡国豪 喻学桥 周卫平

中国临床药理学杂志Issue(20):2080-2083,4.
中国临床药理学杂志Issue(20):2080-2083,4.DOI:10.13699/j.cnki.1001-6821.2015.20.031

与结直肠癌转移相关的微小 RNA研究现状

Review of microRNA related to the metastasis of colorectal cancer

彭永红 1蔡国豪 1喻学桥 1周卫平1

作者信息

  • 1. 海南省人民医院消化外科,海口 570311
  • 折叠

摘要

Abstract

Metastasis is one of the leading cause of death in patients with colorectal cancer.MicroRNA ( miRNA) can regulate epithelial-mesen-chymal transition, oncogenes, tumor suppressor genes and tumor metasta-sis related genes, and combine target gene mRNA by binding to comple-mentary sites to regulate the expression of target genes in post-transcrip-tional, thus regulate the tumor occurrence and development.In recent years, more and more studies show that miRNAs play important roles in the metastasis of colorectal cancer, which is expected to become a new target for the treatment of colorectal cancer.

关键词

结直肠癌/转移/微小RNA/相关性

Key words

colorectal cancer/metastasis/microRNA/relationship

分类

医药卫生

引用本文复制引用

彭永红,蔡国豪,喻学桥,周卫平..与结直肠癌转移相关的微小 RNA研究现状[J].中国临床药理学杂志,2015,(20):2080-2083,4.

基金项目

海南省自然科学基金资助项目 ()

中国临床药理学杂志

OA北大核心CSCDCSTPCD

1001-6821

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