万古霉素对新生儿败血症患儿的临床预后及免疫功能的影响OA北大核心CSCDCSTPCD
Influence of vancomycin on clinical outcomes and immune function of neonatal sepsis
目的 评价万古霉素对新生儿败血症患儿的临床预后及免疫功能的影响.方法 入选53例新生儿败血症患儿为试验组,选取同期在我院产科出生的53例正常新生儿作为对照组. 新生儿败血症患儿用头孢硫脒加哌拉西林/舒巴坦进行治疗,明确耐甲氧西林金黄色葡萄球菌败血症患儿改为静脉滴注万古霉素15 mg·kg-1 ,每天1次,治疗7~10 d,观察新生儿败血症患儿在治疗前后的临床疗效,2组新生儿治疗前后的可溶性白细胞介素-2受体( sIL-2R)、免疫球蛋白G(IgG…查看全部>>
Objective To study the influence of vancomycin on clinical effects and immune function of neonatal sepsis.Methods A total of 53 neonatal sepsis treated in our hospital were selected as the test group, and 53 health normal newborns in the same period in our hospital were selected as the control group.All neonatal sepsis were treated with cefa-thiamidine combined with piperacillin sulbactam, and neonatal sepsis that infected by methicillin-resistant Staphyloco…查看全部>>
陈兴月
海南省人民医院新生儿科,海口 570311
医药卫生
万古霉素新生儿败血症免疫功能不良反应疗效
vancomycinneonatal sepsisimmune functionadverse drug reactionefficacy
《中国临床药理学杂志》 2015 (22)
2184-2186,3
海南省卫生厅医学科研课题基金资助项目(琼卫2013-043号)
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