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点阵CO2激光治疗兔耳增生性瘢痕后P物质的变化

欧阳华伟 谭军 李高峰 雷颖 刘宇

中国美容医学2015,Vol.24Issue(18):31-34,4.
中国美容医学2015,Vol.24Issue(18):31-34,4.

点阵CO2激光治疗兔耳增生性瘢痕后P物质的变化

The change of substance P during treatment of hypertrophic scars in rabbit ear with fractional CO2 laser

欧阳华伟 1谭军 1李高峰 1雷颖 1刘宇2

作者信息

  • 1. 湖南省人民医院 整形&激光美容科 湖南 长沙 410013
  • 2. 湖南省人民医院 病理科 湖南 长沙 410013
  • 折叠

摘要

Abstract

Objective To investigate the change of substance P after fractional CO2 laser on the treatment of hypertrophic scars in rabbit ear. Methods The model of hypertrophic scars in rabbit ear was established,then expression of substance P were tested by immunohistochemical after fractional CO2 laser on the treatment of hypertrophic scars in rabbit ear. Results The score of substance P expression at 1st day was 1.33 ± 0.50,the score of expression at 4th day was 7.67 ± 1.58, xpression score at 7th day was 4.00±1.41,the score of expression at 14th day was 1.56±0.88,there is statistical significance between the two days(P<0.05). Conclusions The change of substance P after fractional CO2 laser on the treatment of hypertrophic scars in rabbit ear shows a trend from rise to decline,it may be related to fractional CO2 laser participating in wound regeneration in situ.

关键词

P物质/点阵CO2激光/增生性瘢痕//瘢痕模型

Key words

substance P/fractional CO2 laser/hypertrophic scar/rabbit/model of hypertropic scar

分类

医药卫生

引用本文复制引用

欧阳华伟,谭军,李高峰,雷颖,刘宇..点阵CO2激光治疗兔耳增生性瘢痕后P物质的变化[J].中国美容医学,2015,24(18):31-34,4.

基金项目

湖南省人民医院仁术基金(2011-15)资助 (2011-15)

中国美容医学

OACSTPCD

1008-6455

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