中国全科医学Issue(30)：3671-3674,4.DOI:10.3969/j.issn.1007-9572.2015.30.008
显微手术夹闭及血管内介入栓塞术治疗高分级大脑中动脉瘤破裂的疗效及安全性研究
Efficacy and Safety of Microsurgical Clipping and Intravascular Interventional Embolization in the Treatment of Poor-grade Middle Cerebral Artery Aneurysm Rupture
摘要
Abstract
Objective To investigate the short -term efficacy and safety of microsurgical clipping and intravascular interventional embolization in the treatment of poor -grade middle cerebral artery aneurysm ( MCAA ) rupture.Methods Enrolled 107 patients with poor grade MCAA rupture who were admitted into the Department of Neurosurgery of the Affiliated Hospital of Chengde Medical University from April 2011 to March 2014.According to surgical methods , we assigned 52 patients into clipping group in which microsurgical clipping was undertaken and assigned 55 patients into intervention group in which intravascular interventional embolization was undertaken.Before and after three months surgeries , Fisher grading and Barthel index (BI) were used to evaluate the prognosis , and the occurrence of complications was observed.Results Before and three months after operation , the two groups were not significantly different in Fisher grading ( P>0.05 ) .The patients of clipping group and intervention group were significantly different in Fisher grading between before and three months after operation ( u=4.687, 5.455, P<0.05).Three months after operation , the BI score was (46.1 ±9.5) for clipping group and was (48.2 ±8.4) for intervention group , with no significant difference between them ( P>0.05 ) .The incidence of complications was 19.2% (10/52) in clipping group and was 23.6% (13/55) in intervention group , with no significant difference between the two groups (P>0.05) .The two groups were not significantly different in the incidence rates of cerebral angiospasm , cerebral infarction, hydrocephalus, and the incidence of the recurrence of rupture (P>0.05) .Conclusion Microsurgical clipping and intravascular interventional embolization have obvious efficacy in the treatment of poor -grade MCAA.The two therapies are not significantly different in Fisher grading , the incidence of complication and BI score.关键词
动脉瘤, 破裂/大脑中动脉/显微外科手术/栓塞, 治疗性/预后Key words
Aneurysm, ruptured/Middle cerebral artery/Microsurgery/Embolization, therapeutic/Prognosis分类
医药卫生引用本文复制引用
呼铁民,杨立军,孟杰,田甜,马志君,张继伟,周敬君,王维兴..显微手术夹闭及血管内介入栓塞术治疗高分级大脑中动脉瘤破裂的疗效及安全性研究[J].中国全科医学,2015,(30):3671-3674,4.基金项目
承德市科学技术研究与发展计划 （）
