摘要
Abstract
Objective To investigate the clinicopathologic features of retroperitoneal cystic melanotic schwannoma in order to improve the level of diagnosis and treatment of such tumor.Methods Selected one patient with retroperitoneal cystic melanotic schwannoma who were admitted into the Department of Oncological Surgery of the First Affiliated Hospital of Gannan Medical University on March 17, 2014.We made a review about clinical data , imaging findings, pathological features and treatment methods , and we conducted a general analysis combining with domestic and overseas literatures .Results Due to the pain in the left rear waist , this 47-year-old male went to see a doctor.A tumor was found beside the psoas muscle of left side by enhanced CT scan , which was closely related to the left kidney.And it was removed by surgical operation.Macroexamination:this tumor was cystic with the size 15.0 cm ×10.0 cm ×10.0 cm, within which much sticky liquid like coffee can be seen.And the capsule wall was 1.0 cm thick, part of which was adhered to peripheral tissues of the left kidney.Examination by optical microscope: cyst wall included few tumor cells , and they were divided into nodular shape by fiber tissues; the tumor cells were fusiform and epithelioid, and much melanin deposition can be seen in the cytoplast.Immunohistochemistry: HMB45, Melan-A, S100, CD57 , Vimmentin and CollagenⅣ were ( +) .Ki -67 was 4% ( +) .Pathological diagnosis: it was a typical Retroperitonea cystic melanotic schwannoma.Conclusion Melanotic schwannoma is a rare soft tissue tumor with the features of neurilemma cells and melanocytes differentiation.Cystic melanotic schwannoma is rare and contains potential malignant biological behavior.And such patients need long -term follow-up.关键词
神经鞘瘤/黑色素/腹膜后肿瘤/诊断/免疫组织化学/预后Key words
Neurilemmoma/Melani/Retroperitoneal neoplasms/Diagnosis/Immunohistochemistry/Prognosis分类
医药卫生
