中国社区医师Issue(32)：24-25,2.DOI:10.3969/j.issn.1007-614x.2015.32.13
培美曲塞或紫杉醇联合顺铂治疗晚期肺腺癌的近期疗效比较
Comparison of the short-term curative effect of pemetrexed or paclitaxel combined with cisplatin in the treatment of advanced lung adenocarcinoma
张琴1
作者信息
- 1. 563000贵州省遵义市第一人民医院肿瘤科
- 折叠
摘要
Abstract
Objective:To compare the short-term curative effect and adverse reaction of pemetrexed or paclitaxel combined with cisplatin in the treatment of advanced lung adenocarcinoma.Methods:40 patients with lung adenocarcinoma in Ⅲ ~Ⅳ period were selected.They were randomly divided into the control group and the observation group with 20 cases in each.After 2 cycles of chemotherapy,the curative effects of patients in two groups were assessed.Results:The total effective rate(90%) of the observation group was significantly better than 70% of the control group(P<0.05).The incidence rates of nausea and vomiting,leukopenia in the observation group were lower than those of the control group(P<0.05).The incidence rates of thrombocytopenia,anemia,liver and kidney function damage were compared,the difference was statistically significant(P<0.05).Conclusion:The treatment effect of using pemetrexed combined with cisplatin for advanced lung adenocarcinoma is good,and the adverse reactions are mild.关键词
培美曲塞/紫杉醇/晚期肺腺癌Key words
Pemetrexed/Paclitaxel/Advanced lung adenocarcinoma引用本文复制引用
张琴..培美曲塞或紫杉醇联合顺铂治疗晚期肺腺癌的近期疗效比较[J].中国社区医师,2015,(32):24-25,2.
