中国比较医学杂志Issue(10)：55-58,4.DOI:10.3969.j.issn.1671.7856.2015.010.013
当归补血汤对辐射损伤小鼠的防护作用
The protective effect of Danggui Buxue decoction on radiation injury in mice
冯璟 1于远望2
作者信息
- 1. 陕西中医药大学医学技术学院，陕西咸阳 712046
- 2. 陕西中医药大学基础医学院，陕西咸阳712046
- 折叠
摘要
Abstract
Objective To observe the protective effect of Danggui Buxue Decoction on 60 Co-γray irradiated mice. Methods The experimental mice were randomly divided into 5 groups ( the normal control group , model group , Danggui Buxue Decoction of low , middle and high dose groups ) .The mouse except the normal control group were irradiated by 60Co-γray and established the radiation-damage model.Peripheral blood neutrophil count (NEUT), the number of bone marrow nucleated cells ( BMC ) , the activity of serum superoxide dismutase ( SOD ) and the serum levels of malondialdehyde ( MDA) were measured .Results Radiation injury in mice of NEUT , BMC and SOD were significantly decreased (P <0.01), MDA were increased (P <0.01).Danggui Buxue Decoction can increase the levels of NEUT , BMC and SOD in mice after radiation injury , decrease the content of MDA .And protective effect of high dose group was better (P <0.01).Conclusions Danggui Buxue Decoction has protective effect on radiation injury in mice .And there is a correlation between the protection effect and dose .关键词
当归补血汤/辐射损伤/防护作用Key words
Danggui Buxue decoction/Radiation injury/Protective effect分类
医药卫生引用本文复制引用
冯璟,于远望..当归补血汤对辐射损伤小鼠的防护作用[J].中国比较医学杂志,2015,(10):55-58,4.
