中国动物传染病学报Issue(3)：51-56,6.
日本血吸虫重组抗原 rSjGALE 对小鼠的免疫保护效果分析
IMMUNOPROTECTIVE EFFECT INDUCED BY RECOMBINANT ANTIGEN RSJGALE OFSCHISTOSOMA JAPONICUM
摘要
Abstract
In a previous study, the immunoprotective effect of UDP-Glucose-4-Epimerase protein of Schistosoma japonicum (SjGALE) was demonstrated, especially in reducing female spawning. In the present study, a combined use of rSjGALE and montanide ISA 206 was tried to see more potent immunoprotection. The results showed that the combination of rSjGALE and montanide ISA 206 induced specific antibodies and reduced liver egg burden, female spawning and hatching rate. However, their immunoprotective activity was not as stable as Freund adjuvant.关键词
日本血吸虫/SjGALE/206 佐剂/免疫保护Key words
Schistosoma japonnicum/SjGALE/montanide ISA 206/immunoprotective effect分类
农业科技引用本文复制引用
曹宇凡,乔洪宾,刘萍萍,杨云霞,石耀军,李浩,刘金明,林矫矫,金亚美..日本血吸虫重组抗原 rSjGALE 对小鼠的免疫保护效果分析[J].中国动物传染病学报,2013,(3):51-56,6.基金项目
国家自然科学基金项目（30800819）；中央级公益性科研院所基本科研业务费项目 （）
