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上海副猪嗜血杆菌分离鉴定及其耐药性分析

张悦 李蓓蓓 魏建超 邵东华 刘珂 石元元 邱亚峰 马志永

中国动物传染病学报Issue(4):25-30,6.
中国动物传染病学报Issue(4):25-30,6.

上海副猪嗜血杆菌分离鉴定及其耐药性分析

ISOLATION AND ANTIBIOTIC RESISTANCE OFHAEMOPHILUS PARASUIS IN SHANGHAI

张悦 1李蓓蓓 1魏建超 1邵东华 1刘珂 1石元元 1邱亚峰 1马志永1

作者信息

  • 1. 中国农业科学院上海兽医研究所,上海 200241
  • 折叠

摘要

Abstract

The aim of this study was to investigate antibiotic resistance inHaemophilus parasuisisolates in Shanghai and thereby to provide data support for antibiotc use in clinical and prevention ofH.parasuisinfection.62 H.parasuis were isolated from 484 samples. Minimal inhibitory concentrations (MICs) of 21 antibiotics were determined by agar dilution method. Susceptibility test showed that all isolates were susceptible to azithromycin, tilmicosin, tiamulin, amikacin, ceftiofur and levofloxacin. At least 90% of them were susceptible to erythromy-cin (60, 96.8%), florfenicol(59, 95.3%), chloramphenicol(60, 96.8%), gentamicin (60, 96.8%), spectinomycin(61, 98.4%), penicillin (57, 91.9%), ampicillin (57, 91.9%) and ciprofloxacin (61, 98.4%). Resistance to tetracycline and enrofloxacin were found in 75.8% (47) and 30.6% (19) of the isolates, respectively. Resistance to at least 2 antibiotics was observed in 37.1% of the isolates. The results of this study indicated that antibiotic resistance inH.parasuis isolates of Shanghai was not too severe. However, resistance to some antibiotics has emerged and enhanced, and continued efforts are needed to monitor the drug susceptibility of the H. parasuisisolates.

关键词

副猪嗜血杆菌/抗菌药/耐药/

Key words

Haemophilusparasuis/antibacterial drugs/antibiotic resistance/swine

分类

农业科技

引用本文复制引用

张悦,李蓓蓓,魏建超,邵东华,刘珂,石元元,邱亚峰,马志永..上海副猪嗜血杆菌分离鉴定及其耐药性分析[J].中国动物传染病学报,2015,(4):25-30,6.

基金项目

国家自然科学基金项目(31302145);中央级公益性科研院所基本科研业务费专项资金项目 (31302145)

中国动物传染病学报

OA北大核心CSTPCD

1674-6422

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