中国心理卫生杂志Issue(11)：812-816,5.DOI:10.3969/j.issn.1000-6729.2015.11.003
伴与不伴焦虑症状抑郁症患者的自杀风险
Risk factors of suicidality in major depressive disorder patients with and without anxious characteristics
辛立敏 1方贻儒 2陆铮 3杨海晨 4胡建 5陈致宇 6黄颐 7孙静 8王小平 9李惠春 10张晋碚 11陈林 12司天梅 13吉振鹏 1张索远 14王君 13刘艳红 13陈大方 13杨甫德 14王刚13
作者信息
- 1. 北京大学第六医院，北京大学精神卫生研究所，卫生部精神卫生学重点实验室 北京大学，北京100191
- 2. 北京回龙观医院，北京 100096
- 3. 上海交通大学附属精神卫生中心心境障碍科，上海200030
- 4. 上海同济大学附属同济医院精神医学科，上海200065
- 5. 深圳精神卫生中心情感障碍科，广东深圳518020
- 6. 哈尔滨医科大学附属第一医院，哈尔滨 150001
- 7. 杭州第七人民医院，杭州310007
- 8. 西川大学华西医院心理卫生中心，成都610041
- 9. 南京医科大学附属脑科医院，南京210029
- 10. 湖南湘雅二院精神卫生研究所，长沙410011
- 11. 浙江大学医学院附属第二医院精神科，杭州310009
- 12. 中山大学附属第三医院心理科，广州510630
- 13. 北京回龙观医院，北京 100096
- 14. 北京大学医学部公共卫生学院，北京100191
- 折叠
摘要
Abstract
Objective:To compare the suicidality risk in major depressive disorder (MDD)patients with and without anxious characteristics,and analyze the risk factors of suicidality in MDD patients. Methods:This was a secondary analysis of the data from the Diagnostic Assessment Service for people with Bipolar Disorders in China (DASP),which was initiated by the Chinese Society of Psychiatry (CSP),from September 1,2010 to February 28, 201 1. Based on the anxious module and suicide module of Mini International Neuropsychiatric Interview (M. I. N. I),1 172 MDD patients were classified as suffering from anxious MDD (n=728,62. 1%)and non-anxious MDD(n=444,37. 9%). Logistic regression was employed to examine the risk factors of suicidality in MDD pa-tients. Results:Among the anxious MDD patients,331 (45. 5%)of them had suicidality risk. And 54(12. 2%)of non-anxious MDD patients had suicidality risk. Compare to the non-anxious group,the anxious MDD patients had significantly higher suicidality risk (P<0. 00 1 ). Logistic regression analysis showed that more frequent depressive episodes (OR=2. 07 ),depressive episodes with psychotic symptoms (OR=2. 0 1 ),comorbid with anxious charac-teristics (OR=3. 18)or melancholic characteristics (OR=2. 90)were associated with suicidality risk in patients with MDD. Conclusion:It indicates that the anxious MDD patients may have higher suicidality risk than non-anx-ious MDD patients,and more frequent depressive episodes,depressive episodes with psychotic symptoms,comorbid with anxious characteristics or melancholic characteristics may be risk factors of suicidality in patients with MDD.关键词
抑郁症/焦虑症状/自杀风险/危险因素Key words
depressive disorder/anxious/suicidality/risk factor分类
医药卫生引用本文复制引用
辛立敏,方贻儒,陆铮,杨海晨,胡建,陈致宇,黄颐,孙静,王小平,李惠春,张晋碚,陈林,司天梅,吉振鹏,张索远,王君,刘艳红,陈大方,杨甫德,王刚..伴与不伴焦虑症状抑郁症患者的自杀风险[J].中国心理卫生杂志,2015,(11):812-816,5.
