中国药房Issue(29)：4066-4068,3.DOI:10.6039/j.issn.1001-0408.2015.29.12
注射用盐酸头孢甲肟与更昔洛韦的配伍稳定性考察Δ
Compatible Stability of Cefmenoxime for Injection with Ganciclovir for Injection
摘要
Abstract
OBJECTIVE:To study the compatible stability of Cefmenoxime for injection with Ganciclovir for injection in 0.9% Sodium chloride injection and 5% Glucose injection. METHODS:At room temperature,the appearance and pH of the mix-tures were observed after Cefmenoxime for injection was compatible with Ganciclovir for injection. HPLC method was adopted to determine the content of them. RESULTS:No significant change was noted for the mixture in appearance and pH value. The con-tent of ganciclovir was more than 98%,but that of cefmenoxime decreased to 75.33%. CONCLUSIONS:Cefmenoxime for injec-tion can not be mixed with Ganciclovir for injection in 0.9%Sodium chloride injection and 5%Glucose injection .关键词
头孢甲肟/更昔洛韦/高效液相色谱法/配伍/稳定性Key words
Cefmenoxime/Ganciclovir/HPLC/Compatibility/Stability分类
医药卫生引用本文复制引用
王建欣,黄志云,郭俊利,杨继章..注射用盐酸头孢甲肟与更昔洛韦的配伍稳定性考察Δ[J].中国药房,2015,(29):4066-4068,3.基金项目
河北省医学科学研究重点课题 （）
