中国药房Issue(30)：4247-4249,3.DOI:10.6039/j.issn.1001-0408.2015.30.25
金乌健骨胶囊的质量标准研究Δ
Study on the Quality Standard of Jinwu Jiangu Capsule
摘要
Abstract
OBJECTIVE:To establish the quality standard of Jinwu jiangu capsule. METHODS:Microscopy was used to identi-fy Panax notoginseng;TLC was used to identify Paeonia lactiflora and Sinomenii Caulis;HPLC was used to determine the content of paeoniflorin. The column was ZORBAX SB-C18 with mobile phase of acetonitrile-0.1% phosphoric acid(13∶87,V/V)at a flow rate of 1.0 ml/min,detection wavelength was 230 nm,column temperature was 30 ℃ and injection volume was 10 μl. RESULTS:Microscopy showed P. notoginseng had obvious features;P. lactiflora and Sinomenii Caulis in preparation were well-separated with clear spots. The linear range of paeoniflorin was 0.014-1.412 μg/μl(r=0.999 2);RSDs of precision,stability and reproducibility tests were lower than 2%;recovery was 95.73%-99.48%(RSD=1.54%,n=6). CONCLUSIONS:The method is simple,accurate and reproducible,and can be used for the quality control of Jinwu jiangu capsule.关键词
金乌健骨胶囊/质量标准/薄层色谱法/高效液相色谱法/芍药苷/三七/白芍/青风藤Key words
Jinwu jiangu capsule/Quality standard/TLC/HPLC/Paeoniflorin/Panax notoginseng/Paeonia lactiflora/Sino-menii Caulis分类
医药卫生引用本文复制引用
周训蓉,杨亮..金乌健骨胶囊的质量标准研究Δ[J].中国药房,2015,(30):4247-4249,3.基金项目
贵州省优秀科技教育人才省长专项资金项目（No.黔省专合字〔2011〕86号）；贵州省中医药管理局中医药、民族医药科学技术研究课题（No.QZYY2013-70）；贵州省科学技术基金项目 （）
