中国药房Issue(32)：4515-4518,4.DOI:10.6039/j.issn.1001-0408.2015.32.18
552例注射用七叶皂苷钠致不良反应/事件及说明书对比分析
Comparative Analysis of 552 Cases of Adverse Drug Reactions/Events Induced by Sodium Aescinate for Injec-tion and Instructions
李强 1王丽2
作者信息
- 1. 郑州市食品药品检验所，郑州 450006
- 2. 河南省食品药品评价中心，郑州 450004
- 折叠
摘要
Abstract
OBJECTIVE:To provide reference for clinical safe administration and drug instruction revision through analyzing 552 cases of ADR/ADE induced by Sodium aescinate for injection. METHODS:Using“aescinate”and“ADR”as search words,re-trieved from CBM,CNKI,VIP and Wanfang database,47 literatures were included according to inclusion and exclusion criteria. The data was extracted and analyzed statistically. The drug instructions of twelve domestic pharmaceutical enterprises were analyzed statistically. RESULTS:The ADR/ADEs may involve multiple organs and systems,the most common reactions were venous irritant reactions as phlebitis,venous injury,etc. The drug instruction lacked some parts of information. CONCLUSIONS:Great impor-tance should be attaches to ADR/ADEs caused by Sodium aescinate for injection,and improvement of the drug instruction to en-sure the safety of drug use in the clinic.关键词
注射用七叶皂苷钠/不良反应/事件/说明书/分析Key words
Sodium aescinate for injection/ADR/ADEs/Instruction/Analysis分类
医药卫生引用本文复制引用
李强,王丽..552例注射用七叶皂苷钠致不良反应/事件及说明书对比分析[J].中国药房,2015,(32):4515-4518,4.
