乳果糖联合枯草杆菌二联活菌治疗功能性便秘的临床观察OA北大核心CSTPCD
Clinical Observation of Lactulose Combined with Bacillus subtilis Bifarous Viable Bacteria in the Treatment of Functional Constipation
目的：观察乳果糖联合枯草杆菌二联活菌治疗功能性便秘的临床疗效与安全性。方法：采用随机双盲对照研究，将60例功能性便秘患者随机分为治疗组28例与对照组32例。两组患者均口服乳果糖，治疗组患者加服枯草杆菌二联活菌，对照组患者加服安慰剂，2周后均停用乳果糖，加服药物直至第4周再停用。比较两组患者治疗前与治疗后第2、4周的排便次数、粪便性状、便秘症状、生活质量及不良反应。结果：两组患者在第2周的排便次数、粪便性状、便秘症状均较治疗前明显改善，差异有统计学…查看全部>>
OBJECTIVE:To observe the clinical efficacy and safety of lactulose combined with Bacillus subtilis bifarous via-ble bacteria in the treatment of functional constipation(FC). METHODS:In a randomized double blind controlled study,60 FC pa-tients were randomly assigned into treatment group(28 cases)and control group(32 cases). Both groups received lactulose orally. Treatment group additionally receive B. subtilis bifarous viable bacteria,and control group addit…查看全部>>
李前龙;古赛
重庆医科大学附属第一医院消化内科，重庆 400016重庆医科大学附属第一医院消化内科，重庆 400016
医药卫生
功能性便秘枯草杆菌二联活菌乳果糖联合用药疗效
Functional constipationBacillus subtilis bifarous viable bacteriaLactuloseDrug combinationTherapeutic efficacy
《中国药房》 2015 (32)
4554-4556,4557,4
评论