摘要
Abstract
OBJECTIVE:To observe therapeutic efficacy and safety of shuxuetong combined with butylphthalide in the treat-ment of elderly acute massive cerebral infarction. METHODS:76 elderly patients with acute massive cerebral infarction selected were randomly divided into observation group and control group,with 38 cases in each group. Control group was treated with bu-tylphthalide,100 ml,bid;observation group was additionally given shuxuetong 6 ml added into 55 Glucose injection 200 ml, ivgtt,qd,on the basis of control group. The NIHSS,coagulation index,hematocrit,platelet aggregation rate and clinical efficacy were observed in 2 groups before and after treatment. RESULTS:After 14 d treatment,NIHSS of observation group [(3.57±0.25) points] was significantly lower than that of control group [(5.98±1.13)points],with statistical significance(P<0.05);after treat-ment,total effective rate of observation group(81.58%)was significantly higher than that of control group(57.89%),with statis-tical significance(P<0.05);platelet aggregation rate [(52.38±3.74)%] and hematocrit [(36.21±3.26)%] of observation group were significantly lower than those of control group,with statistical significance (P<0.05). Before and after treatment,coagula-tion indexes of both groups had no significant change,without statistical significance(P>0.05). No obvious ADR was found in 2 groups. CONCLUSIONS:Shuxuetong combined with butylphthalide is effective in the treatment of elderly acute massive cerebral infarction,and help restore neurological function with good safety.关键词
疏血通/丁苯酞/急性大面积脑梗死Key words
Shuxuetong/Butylphthalide/Acute massive cerebral infarction分类
医药卫生
