中国药房Issue(34)：4844-4846,3.DOI:10.6039/j.issn.1001-0408.2015.34.30
Box-behnken效应面法优选麸炒苍术的炮制工艺
Optimization of Processing Technology for Atractylodes lancea Stir-baking with Bran by Box-behnken Re-sponse Surface Methodology
摘要
Abstract
OBJECTIVE:To optimize the processing technology for Atractylodes lancea stir-baking with bran. METHODS:Us-ing the content of atractylodin,yield of water-soluble extract and ethanol-soluble extract,appearance score as comprehensive in-dex,the effects of excipient amount,stir-baking time and temperature on the quality of A. lancea stir-baking with bran were investi-gated by Box-behnken design-response surface method,so as to optimize the processing technology parameters of A. lancea stir-bak-ing with bran,and verification test were conducted. RESULTS:The optimized parameters were that the excipients amount was 10% medicinal material,stir-baking at 140 ℃ for 3 min;average comprehensive score of verification test was 0.39 (RSD=2.88%,n=3),which was close to predicted value 0.38. CONCLUSIONS:Box-behnken response surface method is reasonable and feasible for the optimization of the processing technology for A. lancea stir-baking with bran.关键词
麸炒苍术/Box-behnken效应面法/炮制工艺/苍术素Key words
Atractylodes lancea stir-baking with bran/Box-behnken response surface method/Processing technology/Atracty-lodin分类
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李萍,刘舸..Box-behnken效应面法优选麸炒苍术的炮制工艺[J].中国药房,2015,(34):4844-4846,3.
