中国药物经济学Issue(3):151-152,2.
抗甲亢药物致粒细胞缺乏症11例临床分析
Clinical analysis of 11 cases of agranulocytosis induced by antithyroid drugs
曾文谊 1林颖 1李军 1陈莉 1黄妙婵1
作者信息
- 1. 广东省东莞市人民医院临床药学科,广东东莞 523018
- 折叠
摘要
Abstract
Objective To investigate the mechanism induced granulocyte cel deficiency antithyroid drug (ATD), to improve the diagnosis and treatment. Methods Against thyroid drugs caused analyzed the clinical data of 11 patients with myeloid deficiency. Results ATD-induced agranulocytosis the disease mostly occurs in the initial treatment of the first 2-3 months or 1-2 months medication again. Comprehensive treatment using disable ATD;granulocyte colony-stimulating factor (G-CSF), broad-spectrum antibiotics, disinfection and isolation, the effect is obvious. Conclusion Accept the ATD patients treated immediately check white blood cel s in the treatment symptoms of fever, sore throat,general malaise, and found that the incidence of agranulocytosis.关键词
甲状腺功能亢进症/粒细胞缺乏症/ATD/不良反应Key words
Thyroid function hyperthyroidism/Agranulocytosis/ATD/Adverse reactions分类
医药卫生引用本文复制引用
曾文谊,林颖,李军,陈莉,黄妙婵..抗甲亢药物致粒细胞缺乏症11例临床分析[J].中国药物经济学,2013,(3):151-152,2.