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抗菌药物不合理使用与药物不良反应发生的相关性

杨文珍

中国药物经济学Issue(11):21-22,2.
中国药物经济学Issue(11):21-22,2.

抗菌药物不合理使用与药物不良反应发生的相关性

The Correlation between the Irrational Use of Antimicrobial Agents and the Occurrence of Adverse Drug Reactions

杨文珍1

作者信息

  • 1. 云南省临沧市镇康县人民医院,云南临沧 677700
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摘要

Abstract

Objective To investigate the relationship between the irrational use of antibiotics and the occurrence of adverse drug reactions.Methods November January 2013 to 2014 Yunnan Province Lincang zhenkang County People's Hospital for diagnosis and treatment of adverse drug reactions in patients with 62 patients were selected to col ect clinical data of the patients,to carry on the statistical analysis to the the use of antibacterial drug type,route of administration,adverse reactions occur rate and adverse reaction of form and location.Results Quinolone induced adverse reaction rate was the highest,fol owed by beta lactam antibiotics;adverse reactions mainly involving the skin and soft tissue.Secondly,for the digestive system;unreasonable use of antibacterial drugs mainly medication for a long time,speed too fast,the dose is too large,the high drug concentration;Pearson correlation analysis showed that,medi-cation for a long time,speed is too fast,excessive dosage,high drug concentration and antibacterial drugs,the adverse reactions were positively correlated.Conclusion In order to reduce the occurrence of adverse reactions,the use of antibiotics should be used to understand the use of drugs,the indications,the possible adverse reactions,and so on.

关键词

抗菌药物/药物不良反应/不合理用药/相关性

Key words

Antimicrobial agents/Adverse drug reactions/Unreasonable use/Correlation

分类

医药卫生

引用本文复制引用

杨文珍..抗菌药物不合理使用与药物不良反应发生的相关性[J].中国药物经济学,2015,(11):21-22,2.

中国药物经济学

1673-5846

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