中国药物评价Issue(5)：277-279,3.
超高效液相色谱法在药物有关物质分析中的应用
Application of Ultra High Performance Liquid Chromatography in the Analysis of Related Substances in Drugs
邬伟魁 1严倩茹1
作者信息
- 1. 梅州市食品药品监督检验所，广东梅州514071
- 折叠
摘要
Abstract
The control of drug related substances is an important guarantee for drug safety and effective.High performance liquid chromatography ( HPLC) is one of the most commonly used methods in the analysis of related substances.In recent years, application of ultra high performance liquid chromatography ( UPLC) in the analysis of related substances in drugs gradually increased.Compared to HPLC method, UPLC method is more efficient, rapid, ensure the chromatographic peak of principal component and the related sub-stances completely separated, and greatly shorten the detection time.In this article, determination of related substances in the raw mate-rial medicine and preparation, simultaneous determination of drug content and related substances by UPLC were discussed, providing ref-erences for the study of the related substances analysis.关键词
超高效液相色谱法/药物/有关物质Key words
Ultra high performance liquid chromatography ( UPLC)/Drug/Related substances分类
医药卫生引用本文复制引用
邬伟魁,严倩茹..超高效液相色谱法在药物有关物质分析中的应用[J].中国药物评价,2015,(5):277-279,3.
