邓金 1周平 1张露 1田双明 1马树花 1伍小敏1
作者信息
- 1. 中南大学湘雅三医院 湖南 长沙 410013
- 折叠
摘要
Abstract
Objective:To evaluate the tissue stiffness of thyroid nodules by ARFI to differentiate benign from malignant thyroid lesions. Method:The ARFI technique was performed in 90 patients with 102 thyroid nodules(75 benign,27 malignant). The values of virtual touch tissue quantication (VTQ)were obtained and analyzed. The area under the curve and cut-off point,both of which were obtained by using a receiver operating characteristic curve analysis,were used to assess diagnostic performance. Final diagnosis was established by histopathology. Result:The VTQ median value of malignant nodules,a benign nodules,and the surrounding thyroid parenchyma was 3.04 m/s,mean(3.43±1.13)m/s,range 2.25-6.90 m/s,2.10 m/s,mean (2.08±0.62)m/s,range 0.72-4.24 m/s,1.91 m/s,mean(1.95±0.377)m/s,range 1.23-2.38 m/s,respectively. The VTQ of thyroid malignant nodules was significant higher than that of the benign thyroid nodules. There were statistical differences between malignant and benign nodules(P<0.001). With a cut-off value of 2.60 m/s for VTQ value,the sensitivity,specificity,accuracy,positive predictive value,negative predictive value for malignancy was 87.0%,88.7%,87.3%,70.6%,and 95.6%,respectively. Conclusion:ARFI can significantly improve diagnosis ability in the differentiation between benign and malignant thyroid nodules,which became a very promising diagnostic technique.关键词
声脉冲辐射力成像/甲状腺结节Key words
Acoustic radiation force impulse imaging/Thyroid nodules
