中国医学创新Issue(9)：118-119,120,3.DOI:10.3969/j.issn.1674-4985.2013.09.064
放疗联合唑来膦酸治疗骨转移癌止痛疗效分析
A Retrospective Analysis of Radiotherapy Combined with Zoledronic Acid for Patients with Metastasis Bone Tumor
陈宝玉 1张鸣竹 1房振羽1
作者信息
- 1. 江苏省兴化市肿瘤医院 江苏 兴化 225700
- 折叠
摘要
Abstract
Objective:To evaluate the effect of radiotherapy combined with zoledronic acid in patients with tumors of bone metastasis. Method:From May 2008 to May 2011,62 patients with bone metastasis were randomly divided into radiotherapy group(31 patients)and radiotherapy combined with zoledronic acid group(31 patients). Radiotherapy group was only treated by radiotherapy. Radiotherapy combined with zoledronic acid group was treated by zoledronic acid 4 mg,once every four weeks,total 4-6 cycles,and combined with radiotherapy,DT 40-50 Gy/20-25 fx/4-5 w,or DT 30 Gy/10 fx/2 w. Result:For the effect of pain-relief,partial response rate of only radiotherapy group and combination group was 71.0%,93.5%(X2=5.42, P<0.05). There were significant differences between the two groups. And for movement capacity improvement,partial response rate of only radiotherapy group and combination group was 61.3%,83.9%(X2=3.97,P<0.05). There were significant differences between the two groups. Conclusion:Radiotherapy combination with zoledronic acid can improve the patients’ life quality. It is worthy of further clinical trial.关键词
骨转移癌/放射治疗/唑来膦酸Key words
Metastasis bone tumour/Radiotherapy/Zoledronic acid引用本文复制引用
陈宝玉,张鸣竹,房振羽..放疗联合唑来膦酸治疗骨转移癌止痛疗效分析[J].中国医学创新,2013,(9):118-119,120,3.
