中国医学创新Issue(9)：122-123,2.DOI:10.3969/j.issn.1674-4985.2013.09.066
CIP2A在慢性粒细胞白血病中的表达及意义
Expression and Role of CIP2A in CML Cells/WANG Shi-song
王石松1
作者信息
- 1. 南阳医学高等专科学校附属医院 河南 南阳 473000
- 折叠
摘要
Abstract
Objective:To investigate the expression and significance of cancerous inhibitor of protein phosphatase 2A(CIP2A)in control group and in different phases of CML.Method:The immunohistochemical SP staining was used to detect expression of CIP2A in control group and in different phases of CML.Result:Expression of CIP2A in CML-AP/BP group was significantly higher than that in control group and that in CML-CP group(P<0.05), expression of CIP2A in control group and CML-CP group had no significant difference(P>0.05).CIP2A in no remission group was significantly higher than that in complete remission group(P<0.05).Conclusion:Overexpression of CIP2A in CML bone marrow mononuclear cells plays an important role in CML blast crisis and prognosis.关键词
蛋白磷酸酶2A癌性抑制因子/慢性粒细胞白血病/免疫组化Key words
CIP2A/CML/Immunohistochemistry引用本文复制引用
王石松..CIP2A在慢性粒细胞白血病中的表达及意义[J].中国医学创新,2013,(9):122-123,2.
