中国医学创新Issue(16)：42-43,2.DOI:10.3969/j.issn.1674-4985.2013.16.020
坎地沙坦联合苯磺酸氨氯地平对高血压蛋白尿的作用探析
Effect of Candesartan Cilexetil Combined with Amlodipine Besylate in Treatment of Proteinuria Reduced by Essential Hypertensive
杜宋耿1
作者信息
- 1. 广东省普宁市普宁华侨医院 广东 普宁 515300
- 折叠
摘要
Abstract
Objective:To explore effect of Candesartan Cilexetil combined with Amlodipine Besylate in treatment of proteinuria reduced by essential hypertension.Method:200 patients with hypertension and proteinuria were randomly divided into combination group(n=100) and single group(n=100)from november 2009 to november 2012.Clinical data of two groups were compared.Result: Decrease amplitude of systolic pressure and diastolic pressure in combination group were greater than those in single group(P<0.05).Combination group were better than single group in decreasing total urinary albumin and blood creatinine level(P<0.05).Conclusion: Candesartan Cilexetil combined with Amlodipine Besylate can decrease blood pressure, and reduce renal perfusion pressure and filtration pressure in different mechanisms to protect kidney and reduce proteinuria.It have good clinical efficacy and fewer adverse reactions in treatment of proteinuria and essential hypertension.关键词
坎地沙坦/高血压/苯磺酸氨氯地平/蛋白尿Key words
Candesartan/Hypertension/Amlodipine Besylate/Proteinuria引用本文复制引用
杜宋耿..坎地沙坦联合苯磺酸氨氯地平对高血压蛋白尿的作用探析[J].中国医学创新,2013,(16):42-43,2.
