中国医学创新Issue(21)：25-26,2.DOI:10.3969/j.issn.1674-4985.2013.21.012
阿托伐他汀钙联合尼可地尔对经皮冠状动脉介入治疗患者的心脏保护作用研究
A Study on Protective Effect of Atorvastatin Calcium Combined with Nicorandil on Myocardium of the Patients Undergoing Percutaneous Coronary Artery Intervention
冯红兵1
作者信息
- 1. 广西柳州市柳铁中心医院 广州 柳州 545007
- 折叠
摘要
Abstract
Objective:To investigate the protective effect of atorvastatin calcium combined with nicorandil of the patients undergoing percutaneous coronary artery intervention. Method:104 patients with unstable angina in our hospital from Jan 2009 to Dec 2012 were randomly divided into two groups, 52 cases for esch one.Torvastatin calcium combined with nicorandil were administrated to the combined treatment group and atorvastatin calcium was administrated to the control group alone before operation. The levels of Troponin I,CK-MB and hs-CRP of the patients in the two groups at 24 h after operation were measured and recorded. Result:The number of cases with positive Troponin I,the number of cases whose level of CK-MB were 2 times higher than the maximum reference value and the level of hs-CRP of the combined treatment group were lower obviously than those of the control group after operation. The differences had statistical significance(P<0.05). Conclusion:Atorvastatin calcium combined with nicorandil can ease postoperative myocardial damage of patients with percutaneous coronary artery intervention,and obviously reduce the level of hs-CRP. It can provide better myocardial preservation and inhibit the flammatory reaction,therefore,it helps to reduce the incidence of cardiac events after percutaneous coronary artery intervention.关键词
阿托伐他丁钙/尼可地尔/经皮冠状动脉介入治疗/心脏保护Key words
Atorvastatin calcium/Nicorandil/Percutaneous coronary artery intervention/Cardiac protection引用本文复制引用
冯红兵..阿托伐他汀钙联合尼可地尔对经皮冠状动脉介入治疗患者的心脏保护作用研究[J].中国医学创新,2013,(21):25-26,2.
