中国医学创新Issue(23)：79-80,81,3.DOI:10.3969/j.issn.1674-4985.2013.23.038
糖尿病肾病患者血清高敏C反应蛋白、抵抗素和糖化血红蛋白水平变化
Levels Serum of High-sensitive C-reactive Protein,Resistin and Glycosylated Hemoglobin in Patients with Diabetic Nephropathy
宿建丽1
作者信息
- 1. 山东省青岛市市北区医院 山东 青岛 266035
- 折叠
摘要
Abstract
Objective:To investigate the level of serum high-sensitive c-reactive protein(hs-CRP),resistin and glycosylated hemoglobin(HbAlc) in patients with diabetic nephropathy.Method:A simple type 2 diabetes group was composed of 32 patients,a group of type 2 diabetes combined with diabetic nephropathy was composed of 38 patients,a control group was composed of 30 healthy people. Nephelometry,double antibody sandwich enzyme-linked immunosorbent assay(ELISA),turbidimetric immunoassay and chemiluminescence were used respectively to detect the contents of the level of hs-CRP,resistin,HbAlc and FINS in blood serum of the subjects. Automatic blood biochemical analyzer was used to detect the contents of fasting serum glucose e(FPG)of the subjects,and insulin resistance index(IRI)was estimated by homeostasis model assessment(HOMA).Result:The levels of hs-CRP,resistin and HbAlc of the simple diabetes group and diabetes combined with nephropathy group were significantly higher than the control group, the differences were statistically significant(P<0.01);the above indicators of the simple diabetes group and diabetes combined with nephropathy group were significantly different(P<0.01). Conclusion:Hs-CRP,resistin and HbAlc are high risk factors for type 2 diabetes mellitus and its nephropathy development.关键词
糖尿病肾病/胰岛素抵抗/高敏C反应蛋白/抵抗素/糖化血红蛋白Key words
Diabetic nephropathy/Insulin resistance/High-sensitive c-reactive protein/Resistin/Glycosylated hemoglobin引用本文复制引用
宿建丽..糖尿病肾病患者血清高敏C反应蛋白、抵抗素和糖化血红蛋白水平变化[J].中国医学创新,2013,(23):79-80,81,3.
