中国医学创新2015，Vol.12Issue(30)：57-60,4.DOI:10.3969/j.issn.1674-4985.2015.30.019
腹腔镜胆囊切除术气腹对糖尿病患者术后肝功能的影响
Influence of Pneumoperitoneum on Liver Function after Operation in Diabetic Patients with Laparoscopic Cholecystectomy
摘要
Abstract
Objective:To investigate the influence of CO2 pneumoperitoneum on liver function in diabetic patients who received laparoscopic cholecystectomy.Method:60 patients who received cholecystectomy in our hospital from January 2013 to December 2014 were selected as the research objects.They were all with gallbladder stones, chronic cholecystitis and diabetes mellitus.They were divided into group Ⅰ,group Ⅱ and group Ⅲ according to the intra-abdominal pressures of CO2 pneumoperitoneum,with each group 20 cases.Group Ⅰ and group Ⅱ were given laparoscopic cholecystectomy with pneumoperitoneum pressures 12 and 15 mm Hg respectively.Group Ⅲ was given open cholecystectomy.1 day before operation and 1,24,48 and 72 hours after operation,venous blood was collected to determine the concentrations of ALT,AST and TBIL in serum.Result:1,24 and 48 hours after operation,the levels of ALT,AST and TBIL in group Ⅰ and group Ⅱ were significantly higher than those before operation and those in group Ⅲ.72 hours after operation,the levels of ALT,AST and TBIL in group Ⅱ were significantly higher than those before operation and those in group Ⅲ.The differences above were all statistically significant(P<0.01).After operation,the levels of ALT,AST and TBIL in group Ⅲ were higher than those before operation,but only 24 hours after operation,the differences were statistically significant(P<0.05).The levels of ALT,AST,and TBIL in group Ⅱ were significantly higher than those in group Ⅰ at all times after operation,the differences were statistically significant(P<0.05). Conclusion:Diabetic patients who use conventional pneumoperitoneum pressure in laparoscopic cholecystectomy have less abnormal liver function than high pneumoperitoneum pressure.关键词
CO2气腹/肝功能/糖尿病Key words
CO2 pneumoperitoneum/Liver function/Diabetes引用本文复制引用
张小斌,周毅,张将,赵俊,杜强..腹腔镜胆囊切除术气腹对糖尿病患者术后肝功能的影响[J].中国医学创新,2015,12(30):57-60,4.基金项目
江西省科技计划项目(201013SB02000) （201013SB02000）
