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以壳聚糖磷酸降解产物制作妇科医用敷料的抑菌实验研究

王勋松 唐俊 黄秀珍 袁水斌 欧阳恭华

中国医学创新2015,Vol.12Issue(30):118-121,4.
中国医学创新2015,Vol.12Issue(30):118-121,4.DOI:10.3969/j.issn.1674-4985.2015.30.039

以壳聚糖磷酸降解产物制作妇科医用敷料的抑菌实验研究

Study on Antibacterial Test of Gynecological Medical Dressings Made by Chitosan Phosphate Degradation Products

王勋松 1唐俊 1黄秀珍 1袁水斌 1欧阳恭华1

作者信息

  • 1. 江西省肿瘤医院 江西 南昌 330029
  • 折叠

摘要

Abstract

Objective:To study the antibacterial effect of the gynecological medical dressings made by chitosan phosphate degradation products.Method:Firstly,the chitosan degradation products were made by phosphoric acid degradation and made into the derived dressings.Then their minimum bacteriostatic concentration (MIC) for standard strains and their antibacterial performance were determined.Result:The MIC of chitosan phosphate degradation products for staphylococcus aureus,escherichia coli and candida albicans were 0.25,0.25 and 0.5 mg/mL respectively.The diameter of inhibition zone of suppository dressings for staphylococcus aureus,escherichia coli and candida albicans were 13,13 and 11 mm respectively,while the diameter of inhibition zone of hydrogel dressings for staphylococcus aureus, escherichia coli and candida albicans were 14,14 and 12 mm respectively.Conclusion:Chitosan phosphate degradation products have certain antibacterial properties,which can be popularized and applied in the production of gynecological medical dressings.

关键词

壳聚糖/医用敷料/抑菌实验

Key words

Chitosan/Medical dressings/Antibacterial test

引用本文复制引用

王勋松,唐俊,黄秀珍,袁水斌,欧阳恭华..以壳聚糖磷酸降解产物制作妇科医用敷料的抑菌实验研究[J].中国医学创新,2015,12(30):118-121,4.

基金项目

江西省卫计委科技计划(20143149) (20143149)

中国医学创新

1674-4985

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