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冠心病患者血尿酸水平与心功能不全的相关性研究

廖方清 吕舜荣 徐继双

中国医学创新Issue(31):56-58,3.
中国医学创新Issue(31):56-58,3.DOI:10.3969/j.issn.1674-4985.2015.31.018

冠心病患者血尿酸水平与心功能不全的相关性研究

Correlation Studies between Serum Uric Acid Level and Cardiac Insufficiency of Patients with Coronary Heart Disease

廖方清 1吕舜荣 1徐继双1

作者信息

  • 1. 广东省海丰县彭湃纪念医院 广东 海丰 516400
  • 折叠

摘要

Abstract

Objective:To analyze correlation between serum uric acid (SUA) and chronic cardiac insufficiency of patients with coronary heart diseases.Method: 325 patients with coronary heart diseases were divided into 2 groups, normal cardiac function group (192 cases) and cardiac dysfunction group (133 cases). According to the New York Heart Association (NYHA) criteria, 133 cardiac dysfunction patients were divided into Ⅱ-Ⅳ grades. The level of serum uric acid was measured by urate oxidase method. The correlation between the level of serum uric acid and cardiac function was analyzed by statistical method.Result: There were statistically significant differences in sex, age between the two groups (P<0.05). The mean serum uric acid level of the normal cardiac function group was (325.87±91.32)μmol/L, and the incidence of hyperuricemia (HUA) was 20.31%. The mean serum uric acid level of the cardiac dysfunction group was (424.85±102.23)μmol/L, and the incidence of HUA was 48.87%. There were statistically significant differences between the two groups (P<0.01). With cardiac functional grade increasing,the level of serum uric acid and the incidence of hyperuricemia gradually increased, and there were significant differences (P<0.01).Conclusion:The mean serum uric acid level in patients with cardiac dysfunction is higher than patients with normal cardiac function group, and with the decline of cardiac function, the mean serum uric acid level elevated, and the incidence of HUA elevated too. There is a positive correlation between the level of serum uric acid and the cardiac functional grade.

关键词

冠心病/血尿酸/心功能不全/相关性

Key words

Coronary disease/Serum uric acid/Cardiac insufficiency/Correlation

引用本文复制引用

廖方清,吕舜荣,徐继双..冠心病患者血尿酸水平与心功能不全的相关性研究[J].中国医学创新,2015,(31):56-58,3.

基金项目

2014年度汕尾市科技计划(社会发展领域)项目 ()

中国医学创新

1674-4985

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