中国医学前沿杂志（电子版）Issue(8)：29-31,3.
沙格列汀联合甘精胰岛素治疗老年2型糖尿病的有效性和安全性研究
The effectiveness and safety of saxagliptin combined with insulin glargine in the treatment of gerontal patients with type 2 diabetes mellitus
摘要
Abstract
ObjectiveTo observe the effectiveness and safety of saxagliptin combined with insulin glargine in the treatment of gerontal patients with type 2 diabetes mellitus.Method60 gerontal patients who were injected insulin glargine or combined with metformin and whose blood glucose were poor controled with HbA1c 8%~11%, were divided into treatment group and control group. Treatment group patients were received saxagliptin combined with insulin glargine (Sax+Gla), control group were received acarbose combined with insulin glargine (Aca+Gla). FBG, 2hBG, HbA1c, insulin dose, adverse reaction were compared before and after the treatment between the two groups.Result24 weeeks after the treatment, FBG、2hBG、HbA1c of the two groups decreased signiifcantly (P<0.05). The incidence of hypoglycemia and other adverse effects were similar (P>0.05). The insulin dose and weight increase in treatment group were lower than control group (P<0.05).ConclusionSaxagliptin combined with insulin glargine is effective and safe for gerontal patients with type 2 diabetes mellitus.关键词
沙格列汀/2型糖尿病/老年患者/有效性/安全性Key words
Saxagliptin/Type 2 diabetes mellitus/Gerontal patient/Effectiveness/Safety引用本文复制引用
高静,李新岩,王敏哲..沙格列汀联合甘精胰岛素治疗老年2型糖尿病的有效性和安全性研究[J].中国医学前沿杂志（电子版）,2015,(8):29-31,3.基金项目
新疆医科大学科创基金 （）
