摘要
Abstract
ObjectiveTo investigate the clinical effect of milrinone in the treatment of chronic pulmonary heart disease.Method134 patients with chronic pulmonary heart disease were randomly divided into observation group and control group, 32 case in each group. Control group patients were treated with conventional therapy, observation group patients were treated with milrinone based on control group, the effective rate, pulmonary function, blood gas index and adverse reaction were contrasted between the two groups.Result The effective rate of observation group was higher than control group (P<0.01). There were no signiifcant differences in FVC, forced expiratory volume (FEV1), pulmonary arterial pressure (PAP), PaCO2 and PaO2 between the two groups before treatment (P>0.05). After treatment, FEV1, PaO2, FVC were signiifcantly higher than before treatment (P<0.05), and observation group was signiifcantly higher than control group (P<0.01), PaCO2 and PAP were significantly lower than before treatment, observation group was significantly lower than control group (P<0.01). There were no signiifcant difference in adverse reaction rate between the two groups (χ2=0.2078,P=0.6485).ConclusionMilrinone can effectively reduce the pulmonary hypertension in patients with pulmonary heart disease, improve lung function and heart function, improve blood oxygen saturation, has curative effects, worthy of clinical application.关键词
米力农/肺源性心脏病/临床疗效Key words
Milrinone/Chronic pulmonary heart disease/Clinical effect