中国癌症防治杂志Issue(1)：50-52,53,4.DOI:10.3969/j.issn.1674-5671.2013.01.13
广西贵港地区乙型肝炎病毒感染及肝细胞性肝癌家族史与肝细胞性肝癌患者住院年龄的相关性分析
Analysis of potential associations of hepatitis B virus infection and family history of hepa-tocellular carcinoma with age at liver cancer diagnosis in Guigang city
摘要
Abstract
Objective To explore potential associations of HBV infection and family history of hepatocellular carcinoma(HCC)with age at HCC diagnosis. Methods A total of 1 365 new patients with HCC treated between 2004 and 2008 at the People's Hospital of Guigang were included in a cross-sectional study,and data were analyzed retrospectively using Excel. Results Patients with a family history of HCC presented the disease at a signif-icantly earlier age than did those with no family history(P<0.05).Age at diagnosis did not differ significantly between patients who were HBsAg-negative and patients who were HBsAg-positive (P=0.738).Among patients with no family history of HCC,age at HCC diagnosis did not differ significantly between those who were HBsAg-positive and those who were HBsAg-negative(P=0.443). However,age at HCC diagnosis of patients with a family history of the disease, regardless of their HBsAg status,was significantly lower than that of HBsAg-negative patients with no family history(P<0.05). Conclusion Among patients with HCC in Guigang City,those with a family history of the disease are diagnosed at an earlier age than are those with no family history,regardless of their HBsAg status.关键词
肝肿瘤/肝细胞性肝癌/肝癌家族史/乙型肝炎病毒感染/临床流行病学Key words
Liver neoplasms/Hepatocellular carcinoma/Family history of HCC/HBV infection/Clinical epidemiology分类
医药卫生引用本文复制引用
刘懿,肖军,莫显伟,何科,徐元兵,刘昌化,陈建思,罗汉传,林源..广西贵港地区乙型肝炎病毒感染及肝细胞性肝癌家族史与肝细胞性肝癌患者住院年龄的相关性分析[J].中国癌症防治杂志,2013,(1):50-52,53,4.基金项目
广西卫生厅科研基金资助项目 （）
