摘要
Abstract
Objective To investigate the clinical efficacy of dobutamine for treatment of severe pneumonia in children and the influence on heart function in children. Methods According to the order of visits the pediatric department of our hospital in March 2013 to June 2014 were treated 82 cases of severe pneumonia complicated with heart failure were divided into study group and control group with 41 cases in each group, the control group with conventionaltherapy combined with dopamine in the treatment, the study group in the control group based on the use ofdobutamine. To improve the situation of children in two groups were compared after two courses of treatment 10 d clinical symptoms, curative effect and symptoms of heart failure. Results The symptoms of pneumonia in study group wereimproved time significantly shorter than the control group ( P ﹤ 0. 05 ); before treatment in two groups of children withcreatine ki-nase, creatine kinase isoenzyme levels did not show significant difference ( P ﹥ 0. 05 ) , the study groupafter treatment and control group had significant difference( P ﹤ 0. 05). Treatment study group and the control group before the TcSaO2 not significant difference( P ﹥ 0. 05), the course of treatment, two groups of children with TcSaO2 compared with those before treatment were gradually improved, and at the same time, the study group improved better than the control group ( P ﹤ 0. 05 ) . Before treatment study group the positive rate of X-ray was 82. 93%, 80. 49% in the control group, the difference between the two groups was not significant ( P ﹥ 0. 05 );the positive rate of two groups after treatmentwere significantly reduced, the 24. 39% study group was significantly lower than the control group 34. 15%( P ﹤ 0. 05 ) . Research group of children with dyspnea, cyanosis, liver, poor peripheral circulation symptom improvement time was signifi-cantly shorter than the control group and the difference was significant ( P ﹤ 0. 05 ) . Study on the efficacy of group significantly better than the control group children distribution ( P ﹤ 0. 05 ) , the researchgroup's total effectiveness is 95. 12% higher than that in the con-trol group but the difference was not significant ( 85. 37%, P ﹥ 0. 05 ) . Conclusion On the basis of conventional therapy combined withdopamine and dobutamine for treatment of severe pneumonia in children with heart failure patients can moresignificantly shorten the treatment time, improve the clinical symptoms, improve the symptoms of heart failure, improve the treatment effect.关键词
多巴酚丁胺/多巴胺/小儿/重症肺炎/心功能/心力衰竭Key words
dobutamine/dopamine/children/severe pneumonia/cardiac function/heart failure分类
医药卫生
