摘要
Abstract
Objective To explore the clinical efficacy of docetaxel and herceptin combined with nursing intervention in treating metastat-ic breast cancer HER-2 strong expression. Methods 150 patients with metastatic breast cancer HER-2 strong expression from March 2011 to May 2014 were randomly divided into study group and control group, 75 casesin each group. The control group simply received docetaxel and herceptin therapy, the study group added nursing interventions. Results 3 months after treatment, fever, rash, bone marrow suppression, gastrointestinal discomfort and other adverse reactions in the study group were lower than those in the control group (χ2=7. 292 1, P=0. 006 9 < 0. 05 ); the KPS and QOL scores of the two groups were significantly higher than before treatment, and the study group was significantly higher than the control group( P < 0. 05);the rates of SD and PD cases in the study group were 6. 67%, 2. 66%, which were lower than 2. 66%, 18. 67% of the control group (χ2=10. 074 6, P=0. 001 5 < 0. 05 ) . Conclusion Docetaxel and herceptin combined with nursing interventions in treating patients with metastatic breast cancer HER-2 strong expression can achieve more significant clinical effect, reduce the incidence of adverse reactions, improve the quality of life of patients, promote body recovery, and is worthy of clinical application.关键词
多西他赛/曲妥珠单抗/转移性乳腺癌/HER-2强表达/护理Key words
docetaxel/herceptin/metastatic breast cancer HER-2 strong expression/nursing分类
医药卫生
