中国医药科学Issue(12)：7-9,3.
育龄期妇女宫颈上皮内瘤变锥切治疗后切缘阳性的高危因素分析
Analysis of the risk factors in cutting edge positive after taper cutting treatment of the childbearing age women cervical intraepithelial neoplasia
摘要
Abstract
Objective To investigate the effect of LEEP and cervical cold knife conization (CKC) for treatment of women of childbearing age of cervical intraepithelial neoplasias after margin risk factors of positive. Methods A retrospective in 2007 January to 2011 November in our hospital were diagnosed by colposcope CIN (including CIN1, CIN2, CIN3) in 265 cases of patients, aged between 30 to 49 years old, after cervical conization after treatment, 32 cases with positive margin, 233 cases with negative margins, follow-up of 1 years, after June, December review of TCT, HPV, if necessary, colposcopy, biopsy and further operation treatment. Results The positive margin group was significantly greater than the negative margin group (P<0.05). HPV load margin positive group was significantly higher than negative margin group; positive margin group in the preoperative TCT results in HSIL (HSIL), there was significant difference with negative margin group (P < 0.05); lesions gland involvement in the percentage of no significant difference between the two groups (P>0.05), diagnosis of CIN level, the diagnosis of CIN3 in positive margin group were significantly more than negative margin group (P < 0.05). Conclusion High HPV load of women of child-bearing age ( ≥ 500), higher severity of TCT ( ≥ HSIL), diagnosis of high level CIN (≥CIN3) is the CIN margin risk factors of positive. Positive margin and tumor recurrence/continued. Before the operation, have experience on the part of patients at high risk for arrangement of the doctor, careful operation, combined with appropriate to expand the scope of operation planning situation, if all causes again conization is not possible, CIN3 patients with positive margin feasible uterus hysterectomy, patients for fertility preservation should be followed up closely.关键词
育龄期/宫颈环形电切术/宫颈冷刀锥切术/切缘阳性/高危因素Key words
Child-bearing age/LEEP/Cervical cold knife conization/Positive margin/Risk factors分类
医药卫生引用本文复制引用
梅丽,刘婷婷,李丽..育龄期妇女宫颈上皮内瘤变锥切治疗后切缘阳性的高危因素分析[J].中国医药科学,2013,(12):7-9,3.基金项目
广东省广州市海珠区科技和信息局医疗卫生指导性科技计划项目（2011-D-02）。 （）
