摘要
Abstract
Objective To explore and compare the clinical curative effects of penehyclidine and atropine on patients with acute organophosphorus pesticide poisoning. Methods 84 patients according to the different treatments divided into observation group and control group (42 cases in each group).The observation group was additionally treated with penehyclidine on the basis of conventional treatment,while the control group was additionally treated with atropine. Results The cure rate,case fatality rate,disappear time of symptoms,medication frequency,total amount of medication,recovery time of cholinesterase, hospitalization time and adverse reactions of the observation group were better than these of the control group with significant differences (P<0.05). Conclusion The clinical curative effect of penehyclidine on patients with acute organophosphorus pesticide poisoning is significant,which can effectively reduce the disappeared time of symptoms and hospitalization time,improve the cure rate and reduce the case fatality rate.It has the advantages of less medication, fast onset of action,long acting time, less adverse reactions,high safety,and high selectivity,which is worthy of clinical popularization and application.关键词
急性有机磷农药中毒/长托宁/阿托品Key words
Acute organophosphorus pesticide poisoning/Penehyclidine/Atropine分类
医药卫生