摘要
Abstract
Objective To investigate the safety and the clinical efficacy of salvianolate in treating of angina pectoris. Methods 80 patients with angina pectoris were randomly divided into control group and observation group according to the suitable for admission.Firstly,the two groups were given antiplatelet adhesion,stability of atherosclerotic plaques and other conventional treatment.The observation group were given Salvia miltiorrhiza polyphenols acid salt on the basis of conventional treatment .The clinical curative effect, life quality and exercise tolerance, heart colour to exceed index and the incidence of adverse reactions were compared between the two groups.Results (1)After the treatment, the total effective rate of control group was 78.95%, was significantly lower than the observation group (92.86%) (P< 0.05). (2)The quality of life score and 6 min walking distance of observation group were better than the control group,the difference was significant between two groups(P<0.05). (3)After the treatment, the LVEF in the observation group was better than the control group (P<0.05).At the same time, the LVEDd, LVESd and LADd in the observation group were also significantly less than the control group, and the differences were significant (P<0.05) . (4)The incidence of adverse reactions of control group was 10.0%, and the observation group was 7.5%,There was no statistically significant difference between them (P>0.05).Conclusion Salvianolate in treating of angina pectoris has a good curative effect, and it can effectively improve the patients quality of life, reduce the incidence of adverse reactions, and it should be to promote in clinic.关键词
冠心病/心绞痛/丹参多酚酸盐/安全性Key words
CHD/Angina pectoris/Salvia miltiorrhiza polyphenols acid salt/Safety分类
医药卫生
