中国真菌学杂志2015，Vol.10Issue(5)：276-278,3.
粉防己碱对白念珠菌生物膜及芽管形成的影响
The effects of tetrandrine on Candida albicans biofilm and germ tube formation
摘要
Abstract
Objective To study the effects of tetrandrine ( Tet) on Candida albicans biofilm and germ tube formation. Methods Using the XTT method to observe the effect of Tet on C.albicans biofilm.0.01,0.1,1μmol/L of Tet and C.albicans suspensions were incubated together,then the rates of bud tube were counted.The experiment was repeated 5 times.Results Tet had obvious inhibitory effects on C.albicans biofilm and the germ tube (P<0.05).The biofilm and germ tube formation inhibition rate was the highest in 1μmol/L of Tet,compared with the negative control group (P<0.05) and the 0.01,0.1μmol/L groups (P<0.05).Conclusions Tet had inhibitory effect on C.albicans biofilm and germ tube formation.关键词
粉防己碱/白念珠菌/芽管/生物膜Key words
tetrandrine/Candida albicans/germ tube/biofilm分类
医药卫生引用本文复制引用
郭兰芳,刘大标,周梦婕,华腾江..粉防己碱对白念珠菌生物膜及芽管形成的影响[J].中国真菌学杂志,2015,10(5):276-278,3.基金项目
镇江市科技计划项目 ( SH2013062) （ SH2013062）
