中国中西医结合外科杂志Issue(2):107-109,3.DOI:10.3969/j.issn.1007-6948.2013.02.001
消栓通脉汤对血瘀湿阻证深静脉血栓形成血管内皮功能的影响
Influence on Vascular Endothelial Function of Blood Stasis and Dampness Retention Syndrome of Deep Venous Thrombosis with Xiaoshuantongmai(消栓通脉)Decoction
摘要
Abstract
Objective To observe the influence on vascular endothelial function of blood stasis and damp⁃ness retention syndrome of deep venous thrombosis(DVT) with Xiaoshuantongmai Decoction. Methods Sixty patients were divided randomly into two groups. The treatment group including 30 cases was treated with Xiaosh⁃uantongmai Decoction, and the control group including 30 cases were treated without decoction. Both groups were given the basic therapy including thrombolysis and activating blood to resolve stagnation. The clinical ef⁃fect and the changes of TXB2、6-keto-PGF1α were observed before treatment and 30 days after treatment. Results In the treatment group, 10 patients were cured and the recovery rate was 33%. While in the control group, 3 patients were cured and the recovery rate was 10%. The treatment group was obviously superior to the control group in therapeutic effect(P<0.05), Comparing with control group, TXB2 content of the treatment group significantly reduced(P<0.01), while 6-keto-PGF1α content significantly increased(P<0.01). Conclusion Xiaoshuantongmai Decoction shows protective effect to vascular endothelial function for the patients with blood stasis and dampness retention syndrome of DVT.关键词
深静脉血栓形成/血瘀湿阻证/消栓通脉汤/血管内皮功能Key words
Deep venous thrombosis/blood stasis and dampness retention syndrome/Xiaoshuantongmai De-coction/vascular endothelial function分类
医药卫生引用本文复制引用
张玉冬,侯玉芬,刘明,张玥,马春媚..消栓通脉汤对血瘀湿阻证深静脉血栓形成血管内皮功能的影响[J].中国中西医结合外科杂志,2013,(2):107-109,3.基金项目
山东中医药科技发展计划项目(2007095) (2007095)