中国执业药师Issue(10)：23-26,4.DOI:10.3969/j.issn.1672-5433.2015.10.006
3种青霉素类抗生素治疗儿科支气管肺炎的成本-效果分析
Cost Effectiveness Analysis of 3 Kinds of Penicillins Antibiotics in Treatment of Pediatric Bronchial Pneumonia
摘要
Abstract
Objective: To study the cost-effectiveness ratio of the treatment of bronchial pneumonia as a common disease in pediatrics with different therapeutic regimens and to find out the most reasonable clinical pathway. Methods: About 281 patients with bronchial pneumonia were chosen from hospitalized patients of pediatrics in our hospital in 2014. They were randomly divided into 3 groups, each group was given penicillin sodium for injection, amoxilinna and clavulanate potassium for injection and piperacillin sodium and tazobactam sodium for injection respectively for antimicrobial therapy and the assessment was made on therapeutic schemes according to the principle of pharmacoeconomics. Results: The cost-effectiveness ratio of penicillin sodium for injection, amoxicillin sodium and clavulanate potassium for injection and piperacillin sodium and tazobactam sodium for injection was 4 846.63 ~4 877.30, 1 985.79 and 2 548.10 yuan/each respectively. The incremental analysis showed that the therapeutic scheme with amoxicillin sodium and clavulanate potassium for injection had an obvious advantage as opposed to piperacillin sodium for injection, the incremental cost-effectiveness ratio of piperacillin sodium and tazobactam sodium for injection was 319.18 ~ 345.53 as opposed to penicillin sodium for injection and 9 905.63 as opposed to amoxilinna and clavulanate potassium for injection. Conclusion: The results showed the using amoxilinna and clavulanate potassium for injection is an optimal therapeutic scheme for antimicrobial treatment of pediatric bronchial pneumonia, with lower treatment cost and better effectiveness. It can be regarded as the most reasonable clinical pathway.关键词
儿科/支气管肺炎/成本-效果比/青霉素类抗生素Key words
Pediatrics/Bronchial Pneumonia/Cost-effectiveness Ratio/Penicillins Antibiotics引用本文复制引用
潘奇澄,陆青云,杨将..3种青霉素类抗生素治疗儿科支气管肺炎的成本-效果分析[J].中国执业药师,2015,(10):23-26,4.基金项目
地区常见病临床路径研究项目（黔东南科合 J 字（2014）4045号） （）
